Protein Agonists, Antagonists and Activators

NMDA (CAS: 6384-92-5)

Catalog #：EBC51019

Biological Activity

Synonyms

N-Methyl-D-aspartic acid, N-Methyl-D-aspartic acid

Chemical Name

(R)-2-(Methylamino)succinic acid

Application

NMDA is a definitiveionotropic NMDA receptor agonist

CAS Number

6384-92-5

Purity

≥99.0%

Molecular Weight

147.1

Molecular Formula

C₅H₉NO₄

SMILES

CN[C@H](CC(=O)O)C(=O)O

Target & IC50

Glutamate NMDA receptor: IC50 = 4150 nM (rat); Glutamate NMDA receptor: EC5050 = 6860 nM (rat); Glutamate (NMDA) receptor subunit zeta 1: EC5050 = 8300 nM (rat)

Shipping

Gel Pack

Storage

Store at -20°C

Preparing Stock Solutions

Molecular Structure

ConcentrationSolventMass	1 mg	5 mg	10 mg
1 mM	6.7967 ml	33.9836 ml	67.9671 ml
5 mM	1.3593 ml	6.7967 ml	13.5934 ml
10 mM	0.6797 ml	3.3984 ml	6.7967 ml
50 mM	0.1359 ml	0.6797 ml	1.3593 ml

Solubility
DMSO: 5 mg/mL (33.98 mM) Water: 30 mg/mL (203.90 mM)

Product Description
NMDA is a synthetic agonist of the NMDA receptor that mimics the binding action of the endogenous ligand glutamate. The NMDA receptor is a voltage-gated ion channel closely involved in memory, in spatial learning and perturbing the normal behavior of this receptor system with NMDA exposure has facilitated elucidation of NMDA receptor-mediated activities.