Dimethyloxaloylglycine (CAS: 89464-63-1)
Catalog #:EBC51087
Biological Activity
Synonyms DMOG, Dimethyloxallyl glycine, N-(methoxyoxoacetyl)-glycine methyl ester
Chemical Name N-(2-Methoxy-2-oxoacetyl)glycine methyl ester
Application Dimethyloxaloylglycine is an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase
CAS Number 89464-63-1
Purity ≥99%
Molecular Weight 175.14
Molecular Formula C₆H₉NO₅
SMILES COC(=O)CNC(=O)C(=O)OC
Target & IC50 prolyl-4-hydroxylase: IC50 = 5.18 μM
Shipping Gel Pack
Storage Store at -20°C
Preparing Stock Solutions Molecular Structure
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 5.7097 ml 28.5486 ml 57.0972 ml
5 mM 1.1419 ml 5.7097 ml 11.4194 ml
10 mM 0.5710 ml 2.8549 ml 5.7097 ml
50 mM 0.1142 ml 0.5710 ml 1.1419 ml
Solubility
DMSO: 17.5 mg/mL (100 mM)
Ethanol: 35 mg/mL (199.84 mM)
Product Description

Dimethyloxaloylglycine is a cell permeable Prolyl 4-hydroxylase (P4H) inhibitor which activates the hypoxia-inducible factor (HIF) in cultured cells. DMOG is reported to delay neuronal cell death caused by trophic factor deprivation through a HIF-1 alpha-independent, glucose-dependent mechanism. 

For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
EbioCell Lifescineces, Inc.   Order:400-117-0038   order@ebiocell.com   Support: tech@ebiocell.com   Web:ebiocell.com