Photo：010-62890160
| Biological Activity | |||||||||||||||||||||||||
| Synonyms | Fingolimod hydrochloride, Fty-720, Fingolimod HCl | ||||||||||||||||||||||||
| Chemical Name | 2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride | ||||||||||||||||||||||||
| Application | FTY720 is a cell-permeable immunosuppressive agent | ||||||||||||||||||||||||
| CAS Number | 162359-56-0 | ||||||||||||||||||||||||
| Purity | ≥98.0% | ||||||||||||||||||||||||
| Molecular Weight | 343.93 | ||||||||||||||||||||||||
| Molecular Formula | C₁₉H₃₃ClNO₂·HCl | ||||||||||||||||||||||||
| SMILES | CCCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N.Cl | ||||||||||||||||||||||||
| Target & IC50 | S1P receptor: IC50 = 0.03 nM | ||||||||||||||||||||||||
| Shipping | Gel Pack | ||||||||||||||||||||||||
| Storage | Store at -20°C | ||||||||||||||||||||||||
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| Solubility | |
| DMSO : 100 mg/mL (290.76 mM) H₂O : 50 mg/mL (145.38 mM) |
| Product Description | |
FTY720 is a sphingosine-1-phosphate receptor modulator that sequesters lymphocytes in lymph nodes, inhibiting their contribution to autoimmune responses. It is derived from myriocin (ISP-1), a fungal metabolite. FTY720 is also reported to be a cPLA2 inhibitor, a ceramide synthase inhibitor, and a cannabinoid receptor antagonist. |
