IQ-1 (CAS: 331001-62-8)
Catalog #:EBC51119
Biological Activity
Synonyms IQ1, Wnt pathway activator
Chemical Name 2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)acetamide
Application IQ-1 is a cell-permeable tetrahydroisoquinolinylidene
CAS Number 331001-62-8
Purity ≥98.0%
Molecular Weight 362.42
Molecular Formula C21H22N4O2
SMILES CC(=O)C1=CC=C(C=C1)N=NC(C2C3=CC=CC=C3CC(N2)(C)C)C(=O)N
Target & IC50 β-catenin/p300
Shipping Gel Pack
Storage Store at -20°C
Preparing Stock Solutions Molecular Structure
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.7592 ml 13.7961 ml 27.5923 ml
5 mM 0.5518 ml 2.7592 ml 5.5185 ml
10 mM 0.2759 ml 1.3796 ml 2.7592 ml
50 mM 0.0552 ml 0.2759 ml 0.5518 ml
Solubility
DMSO: 72 mg/mL (198.66 mM)
Ethanol: 7 mg/mL (19.31 mM)
Product Description

IQ-1 is a selective inhibitor of Beta-catenin/p300 signaling by binding to protein phosphatase 2. It is used to maintain embryonic cell pluripotency in Wnt3a-treated cells and prevent spontaneous differentiation. It is also reported to upregulate the expression of Sox2 and Oct4 transcription factors. 

For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
EbioCell Lifescineces, Inc.   Order:400-117-0038   order@ebiocell.com   Support: tech@ebiocell.com   Web:ebiocell.com