Photo：010-62890160
| Biological Activity | |||||||||||||||||||||||||
| Synonyms | NSC 74859, NSC-74859, S3I201 | ||||||||||||||||||||||||
| Chemical Name | 2-Hydroxy-4-[[2-(4-methylphenyl)sulfonyloxyacetyl]amino]benzoic acid | ||||||||||||||||||||||||
| Application | Stat3 Inhibitor VI, S3I-201 is an inhibitor of Stat3 phosphorylation and dimerization | ||||||||||||||||||||||||
| CAS Number | 501919-59-1 | ||||||||||||||||||||||||
| Purity | ≥99.0% | ||||||||||||||||||||||||
| Molecular Weight | 365.36 | ||||||||||||||||||||||||
| Molecular Formula | C₁₆H₁₅NO₇S | ||||||||||||||||||||||||
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O | ||||||||||||||||||||||||
| Target & IC50 | Stat3: IC50 = 86 μM | ||||||||||||||||||||||||
| Shipping | Gel Pack | ||||||||||||||||||||||||
| Storage | Store at -20°C | ||||||||||||||||||||||||
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| Solubility | |
| DMSO: 36.5 mg/mL (100 mM) |
| Product Description | |
S31-201 is benezoic acid based small molecule, which inhibits the Stat3 transcription factor by blocking the phosphorylation and dimerization events necessary For activation. Many cancers express aberrant behavior in the Stat3 growth factor, making this compound a valuable tool For perturbing the chemistry of such systems. |
