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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 34 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Caspase-7 Rabbit Polyclonal Antibody detects endogenous levels of Caspase-7 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Caspase-7 also known as MCH3, CMH-1, CASP7 is a member of the cysteine-aspartic acid protease (caspase) family. Caspase-7 play a vital role in the apoptotic process by executing programmed cell death. Caspase-7 primarily located in the cytoplasm that activates in response to apoptotic signals, where caspase-7 translocates to the nucleus to cleave specific substrates, including poly(ADP-ribose) polymerase (PARP), thereby facilitating the dismantling of cellular components during apoptosis. Caspase-7′s ability to cleave PARP into an apoptotic fragment underscores its importance in regulating cellular responses to stress and DNA damage, making caspase-7 a key player in maintaining cellular homeostasis and preventing tumorigenesis. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, K562, HEK293 cells, using Caspase-7 Rabbit Polyclonal Antibody (EAB10489) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using Caspase-7 Rabbit Polyclonal Antibody (EAB10489) at 1:100 dilution.
 Immunofluorescence analysis of Human breast cancer tissue, using Caspase-7 Rabbit Polyclonal Antibody (EAB10489) at 1:200 dilution.
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