| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 121 | Human, Mouse, Rat, Monkey |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ATP-Citrate Lyase Rabbit Polyclonal Antibody detects endogenous levels of ATP-Citrate Lyase protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ATP-citrate synthase also known as ATP-citrate lyase, citrate cleavage enzyme is a cytoplasmic homotetramer that belongs to the succinate/malate CoA ligase family, with its gene located on chromosome 17q12-q21. This enzyme plays a crucial role in cellular metabolism by catalyzing the conversion of citrate and CoA into acetyl-CoA and oxaloacetate. Acetyl-CoA is a vital substrate for fatty acid and cholesterol biosynthesis, making ATP-citrate synthase essential for energy production and lipid metabolism. Additionally, ATP-citrate synthase is significant in the biosynthesis of acetylcholine in nervous tissue, highlighting its importance in neurotransmission and overall brain function. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, COS7 cells, using ATP-Citrate Lyase Rabbit Polyclonal Antibody (EAB10632) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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