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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 61 | Human, Mouse, Monkey |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-CD19 (Tyr531) Rabbit Polyclonal Antibody detects endogenous levels of CD19 protein only when phosphorylated at Tyr531. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CD19 is a member of the immunoglobulin gene superfamily. CD19 plays a significant role in B-cell development and function, as CD19 is selectively expressed on the surface of B-lymphocytes. CD19 contains two extracellular immunoglobulin-like domains, which are essential for interaction with other surface proteins and for initiating intracellular signaling pathways. Notably, CD19 forms functional complexes with proteins such as integrin β1, CD21, and CD81, which are vital for regulating B-cell activation, proliferation, and differentiation. Activation of CD19 leads to cross-linking of immunoglobulin chains and recruitment of Src family protein tyrosine kinases, thereby triggering downstream signaling cascades that are critical for B-cell responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7 cells treated with Serum, using Phospho-CD19 (Tyr531) Rabbit Polyclonal Antibody (EAB10677) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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