| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 45 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Doublecortin Rabbit Polyclonal Antibody detects endogenous levels of Doublecortin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Doublecortin also known as DCX is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. Doublecortin plays a vital role in stabilizing microtubules, which is essential for proper migration of neurons during cerebral cortex development. By facilitating transport of neuronal precursors to appropriate locations, Doublecortin ensures formation of a functional and structurally sound brain. Mutations in the DCX gene lead to severe mental retardation and abnormal brain architecture, causing neurodevelopmental disorders such as lissencephaly and double cortex syndrome. Doublecortin maintains structural integrity of neuronal processes, crucial for synaptic plasticity and overall brain function. |
| Product Image Gallery | |
 Western blot analysis of extracts on Raw264.7, 293T cells, using Doublecortin Rabbit Polyclonal Antibody (EAB10364) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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