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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 113 | Human, Mouse, Monkey |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-FLT3 (Tyr589/591) Rabbit Polyclonal Antibody detects endogenous levels of FLT3 protein only when phosphorylated at Tyr589/591. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FLT3 also known as CD135, STK1, FLK2 is a class III receptor tyrosine kinase that regulates hematopoiesis. FLT3 plays a crucial role in hematopoiesis as FLT3 is involved in the regulation of hematopoietic stem and progenitor cell proliferation and differentiation. FLT3 is primarily expressed in CD34+ cells, which are essential for the formation of blood cells, and FLT3 signaling is vital for maintaining the balance between self-renewal and differentiation of these stem cells. The interaction of FLT3 with its ligands can lead to the activation of downstream signaling pathways that promote cell survival and proliferation, making FLT3 a significant target for therapeutic interventions in hematological malignancies. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7 cells treated with Heat shock, using Phospho-FLT3 (Tyr589/591) Rabbit Polyclonal Antibody (EAB10759) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Predicted band size: 113 kDa; Observed band size: 117 kDa |
