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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 59 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-LYN (Tyr507) Rabbit Polyclonal Antibody detects endogenous levels of LYN only when phosphorylated at Tyr507. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LYN also known as JTK8 is a member of the Src family of non-receptor tyrosine kinases. LYN play a crucial role in various cellular processes, including the regulation of immune responses and hematopoiesis. LYN is predominantly expressed in hematopoietic tissues, where LYN is essential for normal immunoglobulin production and the modulation of immune cell signaling. LYN′s activity is tightly regulated, and LYN is typically maintained in an inactive state, becoming activated during specific cellular events, such as mitosis or immune receptor engagement. This regulation is vital for preventing aberrant signaling that could lead to uncontrolled cell proliferation or autoimmune disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293 cells, using Phospho-LYN (Tyr507) Rabbit Polyclonal Antibody (EAB10839) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 59 kDa; Observed band size: 53, 56 kDa |
