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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 83 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | RSK1/2/3/4 Rabbit Polyclonal Antibody detects endogenous levels of RSK1/2/3/4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
The Rsk family of proteins, including Rsk-1, Rsk-2, Rsk-3, and the highly homologous Rsk-4, are intracellular serine/threonine kinases that serve as crucial signaling intermediates in response to ligand-activated receptor tyrosine kinases. Rsk-4 is predominantly expressed in brain and kidney, playing a significant role in normal neuronal development and highlighting importance in neurogenesis and potential implications in neurological disorders. Each Rsk family member possesses two non-identical complete kinase catalytic domains, a unique structural feature enhancing functional versatility in cellular signaling pathways. Rsk family members share similarities with other kinases like p70 S6 kinase, suggesting related regulatory roles and emphasizing interconnectedness in cellular processes. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat cells, using RSK1/2/3/K4 Rabbit Polyclonal Antibody (EAB10880) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 83 kDa; Observed band size: 90 kDa |
