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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 108 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-CSF-1R/c-Fms (Tyr708) Rabbit Polyclonal Antibody detects endogenous levels of CSF-1R/c-Fms only when phosphorylated at Tyr708. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CSF-1R/c-Fms also known as M-CSFR, CD115 is a transmembrane tyrosine kinase receptor. CSF-1R/c-Fms plays a crucial role in the growth and differentiation of myeloid cells. CSF-1R/c-Fms is encoded by the c-Fms proto-oncogene and is predominantly expressed in mononuclear phagocytes, oocytes, decidual cells, trophoblastic cells, and certain myoblasts. CSF-1R/c-Fms mediates the functions of M-CSF, a glycoprotein essential for the proliferation and differentiation of mononuclear phagocytes, including osteoclasts. M-CSF is a significant player in the inflammatory response, regulating the release of pro-inflammatory cytokines from macrophages, thereby influencing immune responses and tissue homeostasis. |
