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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 70 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LCP1 Rabbit Polyclonal Antibody detects endogenous levels of LCP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LCP1(Lymphocyte cytosolic protein 1) also known as L-Plastin is a member of the plastin family of actin-binding proteins. LCP1 plays a crucial role in cytoskeletal organization and is particularly important in regulating cell adhesion and motility, especially in hematopoietic cells. LCP1 expression is notably elevated in various human cancer cell lines derived from solid tumors, highlighting LCP1 involvement in cancer invasion and metastasis. LCP1 ability to modulate leukocyte adhesion is critical for immune responses, and LCP1 phosphorylation status is essential for the regulation of integrin signaling pathways, which are vital for cell communication and movement. |
| Product Image Gallery | |
 Western blot analysis of extracts on PC12 cells, using LCP1 Rabbit Polyclonal Antibody (EAB11672) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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