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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 204 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | KIF1B Rabbit Polyclonal Antibody detects endogenous levels of KIF1B protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
KIF1B is a vital member of the KIF1/Unc104 family of kinesin-like proteins, which are essential for the transport of mitochondria and synaptic vesicles along axons. KIF1B plays a crucial role in maintaining neuronal health by facilitating the distribution of organelles necessary for energy production and neurotransmitter release. KIF1B shows predominant expression in differentiated nerve cells, highlighting its importance in the nervous system. KIF1B is implicated in the transport of synaptic proteins to the cell periphery in neuronal cell axons by interaction with Rab3 guanine nucleotide exchange factor. Mitochondria are also often transported in axons by KIF1B. The human KIF1B gene is located on chromosome 1p36.2, and mutations in this gene can lead to defects in axonal transport, contributing to peripheral neuropathy. |
| Product Image Gallery | |
 Western blot analysis of extracts on THP-1 cells, using KIF1B Rabbit Polyclonal Antibody (EAB14568) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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