| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 55 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | FLIP Rabbit Polyclonal Antibody detects endogenous levels of FLIP protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FLIP also known as CFLAR is a regulator of apoptosis and is structurally similar to caspase-8. FLIP exists in both long and short forms, plays a crucial role in the regulation of apoptosis, a vital process for maintaining cellular homeostasis and preventing uncontrolled cell proliferation. The short form of FLIP features two death effector domains that are homologous to those found in the FAS-associating protein FADD, while the long form shares significant homology with the cysteine protease FLICE and includes an additional caspase-like domain. The long form lacks a catalytic active site and the necessary residues for substrate binding, which distinguishes FLIP from typical caspases. |
| Product Image Gallery | |
 Western blot analysis of extracts on SKOV3, HepG2, SW480 cells, using FLIP Rabbit Polyclonal Antibody (EAB14654) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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