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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 34 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MAGE-A1 Rabbit Polyclonal Antibody detects endogenous levels of MAGE-A1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MAGE-A1 also known as MAGE1 is a member of the MAGEA gene family, which plays a crucial role in the immune response against tumors by encoding tumor-rejection antigens that are recognized by cytotoxic T lymphocytes. MAGE-A1 expression is primarily restricted to tumor tissues, making MAGE-A1 a promising target for cancer immunotherapy, as MAGE-A1 is virtually absent in normal adult tissues, with the notable exceptions of the testis and placenta. This unique expression pattern underscores MAGE-A1′s importance in distinguishing cancerous cells from normal cells, thereby facilitating targeted therapeutic strategies. Furthermore, MAGE-A1 has been shown to interact with various proteins involved in immune modulation, enhancing MAGE-A1′s potential as a target for developing innovative cancer treatments. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2 cells, using MAGE-A1 Rabbit Polyclonal Antibody (EAB14662) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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