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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 103 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HDAC7 Rabbit Polyclonal Antibody detects endogenous levels of HDAC7 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HDAC7(Histone deacetylase 7) is a member of the histone deacetylase family. HDAC7 plays a crucial role in the regulation of gene expression through function as a histone deacetylase, which removes acetyl groups from lysine residues on histones, leading to chromatin condensation and transcriptional repression. This process is vital for maintaining cellular homeostasis and regulating developmental processes, as aberrant histone acetylation can result in uncontrolled gene expression and contribute to various diseases, including cancer. Additionally, HDAC7 interacts with several transcriptional co-repressors, such as mSin3A, which further underscores importance in the formation of transcriptional repression complexes. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, MCF7, PC3 cells, using HDAC7 Rabbit Polyclonal Antibody (EAB14716) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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