| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 76 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Nrf3 Rabbit Polyclonal Antibody detects endogenous levels of Nrf3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Nrf3 also kwown as NFE2L3 is a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. Nrf3 integrates redox and proteostasis cues to modulate transcriptional networks involved in metabolism, differentiation, and ubiquitin–proteasome system regulation, intersecting with antioxidant response element (ARE)-associated signaling. Through these pathways, Nrf3 contributes to context-dependent control of proliferation and survival and is frequently studied for its altered expression or activity in cancer biology and other disorders characterized by dysregulated stress-response signaling. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562, NIH/3T3 cells, using Nrf3 Rabbit Polyclonal Antibody (EAB14734) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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