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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 74 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Rrn3 Rabbit Polyclonal Antibody detects endogenous levels of Rrn3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rrn3 also known as TIF-IA plays a crucial role in the transcription of ribosomal RNA genes by RNA polymerase I, which is essential for ribosome biogenesis and protein synthesis in eukaryotic cells. Rrn3 ensures proper assembly of ribosomes, which are vital for cellular growth and function. In Saccharomyces cerevisiae, Rrn3 is one of the key transcription factors required for rRNA gene transcription, working alongside other factors to facilitate preinitiation complex formation. Rrn3 is functionally conserved across species, with human Rrn3 showing 21% homology to its yeast counterpart, highlighting evolutionary significance. This conservation underscores Rrn3′s importance in maintaining fundamental processes of cellular growth and proliferation across different organisms. |
| Product Image Gallery | |
 Western blot analysis of extracts on NIH/3T3 cells, using Rrn3 Rabbit Polyclonal Antibody (EAB14736) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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