www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 37 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | LDHA Rabbit Polyclonal Antibody detects endogenous levels of LDHA protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
LDHA(Lactate dehydrogenase A) plays a crucial role in cellular metabolism by catalyzing the conversion of L-lactate to pyruvate, a key step in anaerobic glycolysis, which is vital for energy production, especially in tissues with high energy demands like muscle. LDHA serves as a significant biomarker for various conditions, including germ cell tumors, where expression levels can indicate tumor presence and progression. LDHA is predominantly expressed in muscle tissue, highlighting a role in energy production during intense physical activity. The gene encoding LDHA is located on chromosome 11, and mutations or deficiencies in this gene can lead to conditions such as exertional myoglobinuria, underscoring LDHA′s importance in both health and disease. |
| Product Image Gallery | |
 Western blot analysis of extracts on SW480 cells, using LDHA Rabbit Polyclonal Antibody (EAB14792) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
