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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, ELISA | 120 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Toll-like receptor 7/TLR7 Rabbit Polyclonal Antibody detects endogenous levels of Toll-like receptor 7/TLR7 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TLR7(Toll-like receptor 7) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 is often associated with viral infections. Upon activation, TLR7 initiates a signaling cascade that leads to the production of pro-inflammatory cytokines and type I interferons, essential for mounting an effective immune response. This function is particularly important in the context of viral infections, as TLR7 helps the body detect and respond to pathogens early in the infection process. TLR7 is predominantly expressed in immune-related tissues such as the lung, placenta, and spleen, where TLR7 contributes to the regulation of immune responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on Raji, THP-1, Jurkat cells, using Toll-like receptor 7/TLR7 Rabbit Polyclonal Antibody (EAB14431) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 121 kDa; Observed band size: 140 kDa  Immunohistochemistry of paraffin-embedded Human tonsil tissue, using Toll-like receptor 7/TLR7 Rabbit Polyclonal Antibody (EAB14431) at 1:100 dilution.
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