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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 44 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cytokeratin 19 Rabbit Monoclonal Antibody detects endogenous levels of Cytokeratin 19 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cytokeratin 19 also known as Keratin 19, CK19, KRT19 is a member of the keratin family. Cytokeratin 19 plays a crucial role in maintaining the structural integrity and mechanical resilience of epithelial tissues, facilitating cell differentiation and tissue specialization. Located within the cytoskeletal network of the cell, Cytokeratin 19 interacts with other keratins such as KRT8 and binding proteins like plectin and desmoplakin, which are essential for linking the cytoskeleton to cellular junctions and ensuring cellular stability. Cytokeratin 19 undergoes post-translational modifications, including phosphorylation, which regulate filament assembly and disassembly, thereby influencing cellular signaling pathways and dynamics essential for processes like cell migration and division. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562, 4T1 cells, using Cytokeratin 19 Rabbit Monoclonal Antibody (EAB21314) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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