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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC, FC | 65 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 FC=1:10-100 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | MMP-14 Rabbit Monoclonal Antibody detects endogenous levels of MMP-14 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MMP-14 also knonw as MT-MMP-1 is a member of the membrane-type MMP (MT-MMP) subfamily. MMP-14 plays a crucial role in the degradation of extracellular matrix components, such as collagen and gelatin, which is vital for tissue remodeling and repair processes. MMP-14 is a type I membrane protein that not only degrades extracellular matrix components but also activates other MMPs, thereby regulating the turnover of the extracellular matrix. MMP-14 activation is mediated by proprotein convertases, indicating involvement in a cascade that is essential for maintaining tissue homeostasis and responding to pathological conditions. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HT-1080 cells, using MMP-14 Rabbit Monoclonal Antibody (EAB21443) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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