| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 36 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ApoE Rabbit Monoclonal Antibody detects endogenous levels of ApoE protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ApoE(Apolipoprotein E) is a crucial protein found in various cellular locations, including the plasma membrane and cytosol, where ApoE mediates lipid transport and metabolism. The presence of ApoE in plasma lipoproteins is significant for binding, internalization, and breakdown of lipoprotein particles, making ApoE essential for cholesterol and lipid homeostasis. As a ligand for receptors like the LDL receptor and the hepatic apoE receptor, ApoE facilitates the clearance of cholesterol-rich lipoproteins, thus impacting cardiovascular health. ApoE is synthesized in numerous organs, including the liver and brain, and is present in multiple lipoprotein fractions, including VLDL and HDL. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, Human kidney cells, using ApoE Rabbit Monoclonal Antibody (EAB21596) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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