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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 130 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Integrin αE Rabbit Polyclonal Antibody detects endogenous levels of Integrin αE protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Integrin αE also known as Integrin alpha E, CD103, ITGAE plays a crucial role in the immune system by mediating the adhesion of T cells to epithelial cells, particularly in the gut. This interaction is vital for maintaining the integrity of the epithelial barrier and facilitating immune responses in mucosal tissues. Integrin alpha E is primarily located on the surface of activated T cells and is essential for their migration to sites of inflammation. By binding to E-cadherin on epithelial cells, Integrin alpha E helps to regulate the retention of T cells in tissues, which is important for effective immune surveillance and response. The ability of Integrin alpha E to interact with E-cadherin not only underscores its role in cell adhesion but also highlights its significance in the context of autoimmune diseases and inflammatory conditions, where dysregulation of T cell localization can lead to pathological outcomes. |
| Product Image Gallery | |
 Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using Integrin αE Rabbit Polyclonal Antibody (EAB14849) at 1:100 dilution.
 Immunohistochemical analysis of paraffin-embedded Human colon tissue, using Integrin αE Rabbit Polyclonal Antibody (EAB14849) at 1:100 dilution.
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