| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 92 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ACE2 Rabbit Monoclonal Antibody detects endogenous levels of ACE2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ACE2(Angiotensin converting enzyme 2) also known as ACEH is a potent vasopressor hormone. By converting angiotensin II into angiotensin-(1-7), ACE2 helps to counteract the effects of angiotensin II, thereby promoting vasodilation and reducing blood pressure. ACE2 plays a crucial role in the renin-angiotensin system, primarily functioning as a negative regulator of angiotensin II. This balance is vital for maintaining cardiovascular health and fluid homeostasis, making ACE2 an important target for therapeutic interventions in conditions such as hypertension and heart failure. Additionally, ACE2 is expressed predominantly in cardiac, renal, and testicular tissues, which highlights its significance in organ-specific functions and its potential role in various pathophysiological conditions. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse brain, Mouse kidney cells, using ACE2 Rabbit Monoclonal Antibody (EAB21724) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 92 kDa; Observed band size: 120-135 kDa |
