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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 36 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | FosB Rabbit Monoclonal Antibody detects endogenous levels of FosB protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. As a nuclear phosphoprotein, FosB undergoes sophisticated regulation through post-translational modifications, particularly phosphorylation, which fine-tunes FosB′s stability, subcellular localization, and ability to form complexes with Jun family proteins. These modifications prove essential for FosB′s capacity to bind TPA response elements (TREs) in DNA, enabling precise control of genes involved in proliferation, differentiation, and apoptosis. Through this intricate regulatory network responding to growth factors, stress signals, and other molecular cues, FosB serves as a critical coordinator of transcriptional responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Human liver cells, using FosB Rabbit Monoclonal Antibody (EAB21739) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 36 kDa; Observed band size: 48 kDa |
