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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 21 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:50-200 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Histone H1.0 Rabbit Monoclonal Antibody detects endogenous levels of Histone H1.0 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Histone H1.0 also known as H1F0, H1-0 is a member of the H1 family of linker histones. Histone H1.0 plays a crucial role in chromatin structure and function by interacting with linker DNA between nucleosomes, facilitating DNA compaction into higher-order chromatin. Histone H1.0 is expressed in cells undergoing terminal differentiation or those with low rates of division, distinguishing this protein from other somatic H1 histones typically found in proliferating cells. Histone H10 is derived from the intronless gene H1F0, located on chromosome 22q13.1 in humans, and is widely expressed across various tissues in most vertebrates, highlighting an essential role in cellular processes. |
| Product Image Gallery | |
 Western blot analysis of extracts on Human lung cells, using Histone H1.0 Rabbit Monoclonal Antibody (EAB21775) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 21 kDa; Observed band size: 28 kDa |
