| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 49 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cyclin A2 Rabbit Monoclonal Antibody detects endogenous levels of Cyclin A2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cyclin A2 also known as CCNA2 is a member of the highly conserved cyclin family. Cyclin A2 plays a vital role in regulating cyclin-dependent kinases (CDKs) that are essential for cell cycle progression. Cyclin A2 is primarily located in the nucleus, where cyclin A2 binds and activates CDC2 or CDK2 kinases, facilitating the transitions between the G1/S and G2/M phases of the cell cycle. This nuclear localization ensures cyclin A2 availability at the right time and place to promote DNA replication and synthesis, which are critical for cell division. Cyclin A2 is expressed in all tissues tested, contrasting with cyclin A1, which is restricted to germ cells, highlighting cyclin A2′s importance in a wide range of cellular processes. As cells prepare to enter mitosis, cyclin A2 undergoes rapid degradation, underscoring cyclin A2′s role in the precise timing of cell cycle events. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat, C6 cells, using Cyclin A2 Rabbit Monoclonal Antibody (EAB21804) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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