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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 30 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | AMPKβ1 Rabbit Monoclonal Antibody detects endogenous levels of AMPKβ1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
AMPKβ1 also known as PRKAB1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPKβ1 plays a vital role in cellular energy homeostasis. AMPKβ1 is primarily located in the cytoplasm and is essential for the proper functioning of AMPK, as AMPKβ1 helps to stabilize the complex and facilitate activation in response to cellular energy stress. AMPKβ1′s presence in the cytoplasm allows for rapid signaling in response to fluctuations in ATP levels, enabling the cell to adapt metabolic pathways accordingly. By promoting the phosphorylation of key enzymes involved in energy metabolism, such as acetyl-CoA carboxylase and hydroxy-methylglutaryl-CoA reductase, AMPKβ1 helps to maintain energy balance and prevent cellular damage during periods of low energy availability. |
| Product Image Gallery | |
 Western blot analysis of extracts on HEK293, C2C12, PC12 cells, using AMPKβ1 Rabbit Monoclonal Antibody (EAB21805) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 30 kDa; Observed band size: 38 kDa |
