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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IF/ICC | 36 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IP=1:10-100 IF/ICC=1:100-500 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Jun B Rabbit Monoclonal Antibody detects endogenous levels of Jun B protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Jun B is one of the components of the Activator Protein-1 (AP-1) transcription complex that have been implicated in the control ofthe G0/G1 transtion in fibroblasts. Jun B plays a crucial role in regulating gene expression and is a key component of the AP-1 transcriptional complex, which is essential for various cellular processes, including proliferation, differentiation, and apoptosis. Jun B can form homodimers or heterodimers with c-Fos and other members of the Fos gene family, allowing binding to specific DNA sequences and modulation of target gene transcription. Jun B interaction with these proteins and regulation of transcription is vital for cellular responses to growth factors and stress signals, making Jun B an important player in oncogenic processes and cellular signaling pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, C6, K562 cells, using Jun B Rabbit Monoclonal Antibody (EAB21806) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 36 kDa; Observed band size: 43 kDa |
