www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IF/ICC, ELISA | 71 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:5000-20000 IF/ICC=1:200-1000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HDAC10 Mouse Monoclonal Antibody detects endogenous levels of HDAC10 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HDAC10(Histone deacetylase 10) also called HD10 is a member of the class II HDACs, characterized by its N-terminal Hda1p-related catalytic domain and a unique C-terminal leucine-rich domain, which are essential for deacetylase activity and protein-protein interactions, respectively. HDAC10 shuttles between the cytoplasm and nucleus in response to cellular signals, thereby regulating gene expression and participating in various cellular processes. Post-translational modifications of HDAC10, including phosphorylation and ubiquitination, play a crucial role in modulating enzymatic activity, stability, and subcellular localization. Phosphorylation can influence HDAC10′s ability to interact with other proteins and localization within the cell, while ubiquitination may target HDAC10 for proteasomal degradation, thereby regulating levels and activity within the cell. |
| Product Image Gallery | |
 Western blot analysis of extracts on HEK293, HepG2 cells, using HDAC10 Mouse Monoclonal Antibody (EAB22597) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
|
