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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC, FC | 94 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:100-500 FC=1:10-100 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HSPA4/Apg-2 Rabbit Monoclonal Antibody detects endogenous levels of HSPA4/Apg-2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HSPA4 also known as Apg-2 is a member of the heat shock protein 110 family. HSPA4 plays a crucial role in cellular stress responses by acting as a molecular chaperone, facilitating proper folding and assembly of proteins, and preventing aggregation under stress conditions. This function helps maintain cellular homeostasis and protects cells from damage caused by misfolded proteins, which can lead to various diseases, including neurodegenerative disorders. HSPA4 is predominantly located in the cytoplasm and can translocate to the nucleus under stress, highlighting a dynamic role in cellular function and response to environmental changes. HSPA4 interactions with other proteins, such as HSP 70 and HSP 90, underscore significance in the chaperone network, collaborating to ensure protein quality control and cellular resilience. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562 cells, using HSPA4/Apg-2 Rabbit Monoclonal Antibody (EAB21830) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 94 kDa; Observed band size: 110 kDa |
