ACO2 Rabbit Polyclonal Antibody
Catalog #:EAB11032
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, ELISA 85 Human, Mouse, Rat, Canine
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000
Product Information
Conjugate Unconjugate
Specificity ACO2 Rabbit Polyclonal Antibody detects endogenous levels of ACO2 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q99798

Entrez Gene ID

 50

Product Description

ACO2 also known as Aconitate hydratase, Aconitase 2 is a member of the aconitase/IPM isomerase family. ACO2 plays a crucial role in cellular metabolism by catalyzing the reversible conversion of citrate to isocitrate within the tricarboxylic acid cycle, a key pathway for energy production. This enzyme is predominantly located in the mitochondria, where ACO2 helps maintain a critical citrate:isocitrate ratio, which is essential for various metabolic processes. Proper functioning of ACO2 is vital, as ACO2 not only influences energy production but also impacts the regulation of metabolic intermediates that can affect cell signaling and growth. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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