| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 32 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ATP1B3 Rabbit Polyclonal Antibody detects endogenous levels of ATP1B3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ATP1B3 also known as beta 3 Sodium Potassium ATPase belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. ATP1B3 plays a vital role in regulating ion gradients by transporting sodium and potassium ions across the membrane. Proper functioning of ATP1B3 is critical for various physiological processes, including maintenance of resting membrane potential, cellular volume regulation, and facilitation of secondary active transport mechanisms. Disruption of ATP1B3 function can lead to severe cellular dysfunction and is implicated in various pathophysiological conditions, including hypertension and heart failure. The β subunit of Na+/K+-ATPase complex not only aids in correct folding and membrane insertion of the α subunit but also plays a significant role in overall stability and activity of the enzyme, making ATP1B3 a key target for research in cellular physiology and disease mechanisms. |
| Product Image Gallery | |
 Western blot analysis of extracts on NIH/3T3, PC12 cells, using ATP1B3 Rabbit Polyclonal Antibody (EAB11708) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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