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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 107 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ERAP1 Rabbit Polyclonal Antibody detects endogenous levels of ERAP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ERAP1(Endoplasmic reticulum aminopeptidase 1) is is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. ERAP1 plays a vital role in processing antigenic precursors for major histocompatibility complex (MHC) class I peptide presentation. Specifically, ERAP1 trims peptides to the optimal length of eight to eleven amino acids, which is essential for effective immune recognition and response. ERAP1 is induced by interferon-g and is encoded by the ARTS1 gene located on human chromosome 5q15. In addition to antigen processing, ERAP1 is involved in the inactivation of several bioactive peptides, such as angiotensin II, which may influence blood pressure regulation. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc, HepG2 cells, using ERAP1 Rabbit Polyclonal Antibody (EAB11710) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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