STAMBP Rabbit Polyclonal antibody
Catalog #:EAB14898
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB 48 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity STAMBP Rabbit Polyclonal antibody detects endogenous levels of STAMBP protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

O95630

Entrez Gene ID

10617

Product Description

STAMBP also known as AMSH is a 424 amino acid protein that belongs to the peptidase M67C family and is ubiquitously expressed in various tissues. STAMBP functions as a zinc metalloprotease that specifically cleaves ′Lys-63′-linked polyubiquitin chains, which is essential for regulating protein degradation and cellular signaling pathways. By opposing ubiquitin-dependent sorting of receptors to lysosomes, STAMBP plays a significant role in signal transduction related to cell growth and induction of Myc mediated by interleukin-2 and granulocyte-macrophage colony-stimulating factor. STAMBP enhances bone morphogenetic protein signaling by counteracting inhibitory effects of Smad6 and Smad7, making STAMBP a vital player in various cellular processes.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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