α-Internexin Rabbit Polyclonal Antibody
Catalog #:EAB14899
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, ELISA 55 Human, Mouse, Rat
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000  
IHC-P=1:50-300
Product Information
Conjugate Unconjugate
Specificity α-Internexin Rabbit Polyclonal Antibody detects endogenous levels of α-Internexin protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q16352 

Entrez Gene ID

9118

Product Description

α-Internexin also known as INA is a brain-specific type IV intermediate filament protein predominantly found in the central nervous system, where α-internexin plays a crucial role in maintaining neuronal structure and function. This protein is essential for the formation of a filamentous network that supports axonal integrity, particularly during the critical stages of brain development. The head domain of α-internexin is vital for self-assembly, which is necessary for the stability of neuronal cells. Notably, α-internexin expression peaks during late embryogenesis and decreases into adulthood, indicating significant involvement in the regulatory processes that govern brain maturation. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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