| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 55 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | AtgL Rabbit Polyclonal Antibody detects endogenous levels of AtgL protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
AtgL also known as PLNPA2 is an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. AtgL plays a crucial role in lipid metabolism by catalyzing the hydrolysis of stored triglycerides in adipose tissue, thus facilitating the mobilization of fatty acids for energy production. This process is particularly important in energy homeostasis and metabolic regulation, as AtgL activity is tightly regulated by hormonal signals, such as insulin, which inversely modulates the expression of AtgL and adiponutrin (ADPN). AtgL consists of 486 amino acids and features a highly conserved N-terminal patatin domain, which is essential for lipase activity, along with a glycine-rich region and specific active site motifs that are critical for enzymatic function. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2 cells, using AtgL Rabbit Polyclonal Antibody (EAB11449) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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