| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 47 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ACTL6B/BAF53B Rabbit Polyclonal Antibody detects endogenous levels of ACTL6B/BAF53B protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
BAF53B also known as ACTL6B is a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. BAF53B regulate nucleosome positioning and chromatin accessibility. BAF53B supports transcriptional programs required for neuronal differentiation, dendritic and synaptic maturation, and activity-dependent gene regulation by coordinating with other BAF components to modulate enhancer and promoter usage. Through these epigenetic functions, ACTL6B is linked to pathways controlling neurodevelopmental timing, neuronal connectivity, and plasticity. Genetic and functional perturbations of ACTL6B/BAF53B have been associated with neurodevelopmental disorders and altered neuronal gene expression states relevant to models of cognitive and behavioral phenotypes. |
| Product Image Gallery | |
 Western blot analysis of extracts on A431 cells, using ACTL6B/BAF53B Rabbit Polyclonal Antibody Antibody (EAB11714) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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