| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 58 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ACVR2B Rabbit Polyclonal Antibody detects endogenous levels of ACVR2B protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ACVR2B also known as ACTR-IIB plays a crucial role in the transforming growth factor beta (TGF-β) signaling pathway, which is essential for regulating various cellular processes, including cell differentiation, proliferation, and apoptosis. ACVR2B is primarily located on the cell membrane, where ACVR2B interacts with other receptor types to form a signaling complex that transmits extracellular signals into the cell, thereby influencing gene expression and developmental processes. ACVR2B′s location in the cell enables precise regulation of signaling pathways vital for maintaining cellular homeostasis and responding to environmental cues. Dysregulation of ACVR2B has been implicated in various diseases, including cancer and fibrotic disorders, highlighting ACVR2B′s significance as a therapeutic target. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using ACVR2B Rabbit Polyclonal Antibody (EAB11715) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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