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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 57 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ACVR1A Rabbit Polyclonal Antibody detects endogenous levels of ACVR1A protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ACVR1A also known as ACTR-I, ACVR1 plays a crucial role in the signaling pathways of the transforming growth factor beta superfamily, which is essential for regulating various cellular processes such as gene expression, cell differentiation, and morphogenesis. ACVR1A protein interacts with type II receptors to form a heteromeric complex that is vital for the activation of downstream signaling cascades. This interaction is particularly important in the brain, where both receptor types are highly expressed, influencing neural development and function. ACVR1A protein′s ability to mediate distinct effects based on ligand concentration underscores its significance in cellular communication and the potential implications in developmental biology and disease states. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2 cells, using ACVR1A Rabbit Polyclonal Antibody (EAB14904) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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