| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 57 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ACVR1B Rabbit Polyclonal Antibody detects endogenous levels of ACVR1B protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ACVR1B also known as ALK-4, ACTR-IB is an activin A type IB receptor. ACVR1B plays a crucial role in the signaling pathways of the transforming growth factor beta superfamily, which are essential for various cellular processes, including cell differentiation and tissue homeostasis. Specifically, ACVR1B is located on the cell membrane, where ACVR1B forms a heteromeric complex with type II receptors, facilitating the binding of activin and initiating downstream signaling cascades. This localization is vital as ACVR1B allows for the precise regulation of gene expression and cellular responses to environmental cues, impacting developmental processes and cellular functions. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293, Mouse heart cells, using ACVR1B Rabbit Polyclonal Antibody (EAB14905) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using ACVR1B Rabbit Polyclonal Antibody (EAB14905) at 1:200 dilution.
 Immunofluorescence analysis of Hela cell, using ACVR1B Rabbit Polyclonal Antibody (EAB14905) at 1:200 dilution.
|
