| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 39 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cdc123 Rabbit Polyclonal Antibody detects endogenous levels of Cdc123 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cdc123 (Cell division cycle protein 123) also known as D123 is a crucial 336 amino acid cytoplasmic protein that plays a significant role in regulating the cell cycle. Cdc123 is predominantly expressed in tissues such as the thymus, spleen, ovary, testis, small intestine, and leukocytes, highlighting its importance in various biological processes. The primary function of Cdc123 is to destabilize checkpoint with forkhead and ring finger domain (Chfr) proteins, which, if allowed to accumulate, can inhibit the transition from the G1 to S phase of the cell cycle. By preventing the buildup of Chfr proteins, Cdc123 facilitates the progression of cells into the S phase, thereby promoting normal cell division. |
| Product Image Gallery | |
 Western blot analysis of extracts on A431, COLO205 cells, using Cdc123 Rabbit Polyclonal Antibody (EAB11733) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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