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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 83 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:50-200 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Factor XIIIa Rabbit Monoclonal Antibody detects endogenous levels of Factor XIIIa protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Factor XIII A plays a crucial role in the final stages of the coagulation cascade, where Factor XIII A catalyzes the cross-linking of fibrin, thereby stabilizing the fibrin clot and enhancing resistance to fibrinolysis. This function is vital for effective hemostasis, particularly following tissue injury, as Factor XIII A ensures that the clot remains intact long enough for tissue repair processes to occur. Factor XIII A exists in plasma as a heterotetramer composed of two A subunits and two B subunits, with the A subunits responsible for enzymatic activity. Understanding Factor XIII A structure and function is essential for elucidating Factor XIII A′s role in coagulation disorders and developing targeted therapies for conditions related to abnormal clotting. |
| Product Image Gallery | |
 Western blot analysis of extracts on Human plasma cells, using Factor XIIIa Rabbit Monoclonal Antibody (EAB21954) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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