www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 12 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IGKC/Kappa light chain Rabbit Polyclonal Antibody detects endogenous levels of IGKC/Kappa light chain protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IGKC also known as Ig κ chain plays a crucial role in immune response, as one of two types of light chains forming part of immunoglobulin structure, essential for specificity and functionality of antibodies. Immunoglobulins, composed of two identical heavy chains and two identical light chains, are vital for recognizing and binding to antigens, facilitating their removal from the body. Kappa light chain presence influences overall stability and affinity of antibodies for target antigens. In humans, kappa light chain genes are located on chromosome 2, and their rearrangement during B cell development creates diverse antibody repertoires capable of responding to various pathogens. Unique genetic combinations of heavy and light chains enable production of antibodies with specific binding sites, fundamental for effective immune responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on K562 cells, using IGKC/Kappa light chain Rabbit Polyclonal Antibody (EAB11945) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
