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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 78 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | hnRNP M Rabbit Polyclonal Antibody detects endogenous levels of hnRNP M protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
hnRNP M also known as NAGR1, HNRNPM is a member of the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). hnRNP M plays a crucial role in pre-mRNA splicing, a vital process that ensures the correct maturation of mRNA before translation into proteins. hnRNP M is primarily located in the nucleus, where hnRNP M participates in the assembly of spliceosomal complexes, which are essential for the removal of introns from pre-mRNA. Proper functioning of hnRNP M is important because any dysregulation in splicing can lead to various diseases, including cancer and neurodegenerative disorders. hnRNP M is also involved in stress-induced transient splicing arrest, highlighting hnRNP M′s role in cellular responses to environmental changes. |
| Product Image Gallery | |
 Western blot analysis of extracts on HT29 cells, using hnRNP M Rabbit Polyclonal Antibody (EAB11777) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue, using hnRNP M Rabbit Polyclonal Antibody (EAB11777) at 1:100 dilution.
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