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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IF/ICC | 41 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IF/ICC=1:50-200 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HLA-A Rabbit Monoclonal Antibody detects endogenous levels of HLA-A protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HLA-A belongs to the HLA class I heavy chain paralogues. HLA-A plays a crucial role in the immune response by presenting peptide antigens to T lymphocytes, which is essential for the activation of adaptive immunity. Located on the surface of nearly all nucleated cells, HLA-A molecules are vital for the recognition of infected or malignant cells by cytotoxic T cells, thereby facilitating the elimination of these cells from the body. The structure of HLA-A consists of a membrane-anchored heavy chain that forms a heterodimer with beta-2-microglobulin, allowing for presentation of peptides derived from intracellular proteins. The polymorphic nature of HLA-A, with hundreds of alleles identified, contributes to the diversity of immune responses among individuals, making HLA-A a key factor in transplantation compatibility and susceptibility to autoimmune diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on A549, THP-1, Raji, Jurkat cells, using HLA-A Rabbit Monoclonal Antibody (EAB22024) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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