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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 21 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ITPA Rabbit Polyclonal Antibody detects endogenous levels of ITPA protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ITPA is also known as ITPase is a 194 amino acid protein. ITPA plays a crucial role in nucleotide metabolism by catalyzing the conversion of inosine triphosphate (ITP) and deoxyinosine triphosphate (dITP) into inosine monophosphate (IMP) and diphosphate. This enzymatic activity is vital for maintaining the balance of nucleotide pools within the cell, as an excess of ITP can lead to cellular dysfunction and has been implicated in various pathological conditions. ITPA is predominantly localized in the cytoplasm and is highly expressed in tissues such as the heart, liver, sex glands, thyroid, and adrenal glands. Deficiencies in ITPA can result in an accumulation of ITP in erythrocytes, leukocytes, and fibroblasts, which is thought to be inherited and can lead to significant metabolic disturbances. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using ITPA Rabbit Polyclonal Antibody (EAB14472) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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